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Brand Name:

Daplozmet XR

Generic Name:

Dapagliflozin + Metformin HCI

Composition:

Daplozmet XR 5mg/500mg:Each bi-layered film-coated tablet contains: Dapagliflozin as Propanediol Monohydrate (immediate release) 5mg Metformin HCI (extended release) 500mg

Daplozmet XR 5mg/1000mg Tablet: Each bi-layered film-coated tablet contains: Dapagliflozin as Propanediol Monohydrate (immediate release) 5mg Metformin HCI (extended release) 1000mg

Daplozmet XR 10mg/500mg Tablet: Each bi-layered Film-coated tablet contains: Dapagliflozin as Propanediol Monohydrate (immediate release) 10mg Metformin HCI (extended release) 500mg

Daplozmet XR 10mg/1000mg Tablet: Each bi-layered Film-coated tablet contains: Dapagliflozin as Propanediol Monohydrate (immediate release) 10mg Metformin HCI (extended release) 1000mg

DESCRIPTION:

It contains Dapagliflozin, a SGLT2 inhibitor, and Metformin HCI, a biguanide.

INDICATIONS:

Indications:
It is indicated as an adjunct to diet and exercise to improve Glycaemic control in adults with type 2 diabetes mellitus:
In patients insufficiently controlled on their maximally tolerated dose of metformin alone
In combination with other medicinal products for the treatment of diabetes in patients insufficiently controlled with metformin and these medicinal products
In patients already being treated with the combination of Dapagliflozin and metformin as separate tablets.
Dapagliflozin is indicated to reduce:
The risk of hospitalization for heart failure in adults with type 2 diabetes mellitus and established cardiovascular disease (CVD) or multiple cardiovascular (CV) risk factors.
The risk of cardiovascular death and hospitalization for heart failure in adults with heart failure (NYHA class II-IV) with reduced ejection fraction.
The risk of sustained estimated glomerular filtration rate decline, end-stage kidney disease, cardiovascular death, and hospitalization for heart failure in adults with chronic kidney disease at risk of progression.

PRESENTATION:

Daplozmet XR 5/500mg Tablets:
Alu. Alu. Blister pack of 2 x 7’s.
Daplozmet XR 5/1000mg Tablets:
Alu. Alu. Blister pack of 2 x 7’s.
Daplozmet XR 10/500mg Tablets:
Alu. Alu. Blister pack of 2 x 7’s.
Daplozmet XR 10/1000mg Tablets:
Alu. Alu. Blister pack of 2 x 7’s.

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