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DESCRIPTION:

Azipos (Azithromycin) is a nitrogen-containing macrolide (azalide)

COMPOSITION:

Azipos 250mg Capsule

Each capsule contains: Azithromycin (as Dehydrate) 250mg

Azipos 500mg Capsule

 Each capsule contains: Azithromycin (as Dehydrate) 500mg

INDICATIONS:

Acute bacterial exacerbations of chronic bronchitis, otitis media, Pharyngitis & tonsillitis, uncomplicated skin and skin structure infections, mild to moderate typhoid due to multiple antibacterial resistant organisms, community acquired pneumonia with low to moderate severity, community acquired pneumonia with high severity, antibacterial prophylaxis for insertion of intrauterine device, prevention of secondary case of invasive group a streptococcal infection in patients who are allergic to penicillin, uncomplicated Gonorrhea, Urethritis and cervicitis due to Chlamydia trachomatis or Neisseria gonorrhea and Genital ulcer disease in men due to Haemophilus ducrevi (chancroid).

DOSAGE AND ADMINISTRATION:

In acute bacterial exacerbations of chronic bronchitis: 500 mg once daily for 3 days or 500 mg as a single dose on day 1, followed by 250 mg once daily on days 2 through 5. In acute bacterial sinusitis: 500 mg once daily for 3 days. In pharyngitis/tonsillitis (second line therapy): 500 mg as a single dose on day 1, followed by 250 mg once daily on days 2 through 5. In otitis media: 500 mg once daily for 3 days; Alternatively, initially 500 mg once daily for 1 day, then 250 mg once daily for 4 days. In uncomplicated skin and skin structure infections: 500 mg as a single dose on day 1, followed by 250 mg once daily on days 2 through 5. In mild to moderate typhoid due to multiple antibacterial resistant organisms: Adult Dose; 500 mg once daily for 7 days. Child 6 months and over: 10 mg/kg (to a maximum of 500 mg) once daily for 7 days. In community acquired pneumonia, low to moderate severity: 500 mg once daily for 3 days.

 Alternatively, initially 500 mg once daily for 1 day, then 250 mg once daily for 4 days. In community acquired pneumonia, high severity: Initially 500 mg once daily intravenously for at least 2 days, then 500 mg once daily for a total duration of 7-10 days. In antibacterial prophylaxis for insertion of intrauterine device: one single 1000 mg dose. In prevention of secondary case of invasive group, a streptococcal infection in patients who are allergic to Penicillin: Child 6 months to 11 years, 12 mg/kg once daily (maximum per dose 500 mg) for 5 days. Child 12-17 years & Adult, 500 mg once daily for 5 days. In uncomplicated Gonorrhea: one single 1000 mg dose. In urethritis and cervicitis: one single 1000 mg dose. In genital ulcer disease in men (chancroid): one single 1000 mg dose. The pediatric dose in respiratory tract infections, otitis media, skin and soft tissue infections: Child 6 months to 17 years: 10 mg/kg once daily (maximum per dose 500 mg) for 3 days. Child 6 months to 17 years (body weight 15-25 kg):200 mg once daily for 3 days. Child 6 months to 17 years (body weight 26-35 kg): 300mg once daily for 3 days. Child 6 months to 17 years (body weight 36-45 kg): 400 mg once daily for 3 days.

CONTRAINDICATIONS:

It is contraindicated in patients with known hypersensitivity to azithromycin, erythromycin or any macrolide or ketolide drug. It is contraindicated in patients with history of cholestatic jaundice/hepatic dysfunction associated with prior use of azithromycin.

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