It is a synthetic, non-chiral, quaternary ammonium compound. It is sparingly soluble in water and soluble in methanol. The dry powder formulation within the Tiovair capsule is intended for oral inhalation only. The drug substance, tiotropium bromide monohydrate, is an anticholinergic with specificity for muscarinic receptors.
Tiovair Rotacaps: Each capsule contains: Tiotropium (as Bromide Monohydrate) 18 mcg
Tiovair is indicated as a long-term maintenance treatment of bronchospasm associated with chronic obstructive pulmonary disease (COPD), and for reducing COPD exacerbations.
DOSAGE & ADMINISTRATION:
For oral Inhalation only Inhalation of the powder contents of a single TIOVAIR capsule (18 mcg) once daily CONTRAINDICATIONS Hypersensitivity to tiotropium, ipratropium or any components of Tiovair capsules
Tiotropium bromide inhalation powder is contraindicated in patients with hypersensitivity to tiotropium, atropine or its derivatives, e.g. ipratropium or oxitropium or to the excipient lactose monohydrate.
Available as dry powder inhalation capsules. Tiovair: Tiotropium 18 mcg Each sale pack contains 20 dry powder inhalation capsules.