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Artrodar Product Information Leaflets
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ARTRODAR® (Diacerein) is Symptomatic slow acting drugs for osteoarthritis (SYSADOA).


ARTRODAR® 50 mg capsules contains Diacerein 50 mg.


Treatment of degenerative joint diseases (osteoarthritis & related diseases) and also symptomatic relief in long-term treatment of osteoarthritis.


The usual dosage regimen for Diacerein is one capsule taken orally twice a day with the main meals for six months. However, as Diacerein may cause loose stools during the first 2 weeks of treatment, it is recommended to start the treatment with one capsule of Diacerein per day taken orally with evening meal for 4 weeks. Once the patient has become accustomed to the medication, the dose should be increased to 2 capsules per day, taken orally with meals.


Diacerein should not be administered to patients with known hypersensitivity to the drug itself or to those with previous episodes of hypersensitivity to anthraquinone derivatives. Temporary treatment suspension must be considered in case of antibiotic therapy, which may affect intestinal flora and kinetics. The benefit / risk ratio of administering Diacerein to patients with previous episodes of enterocolic disturbances, especially irritable colon, must be considered. Diacerein is contraindicated in subjects with severe renal insufficiency.


Loose stools (7%) associated with Diacerein treatment. The symptoms may appear within the first few days of treatment. In most cases these symptoms resolve spontaneously with continuing treatment. The intake of Diacerein may sometimes result in a more intense yellow coloring of the urine. This is typical of the type of compound and is of no clinical significance.


ARTRODAR® 50mg capsules: Pack of 30 capsules.


Diacerein should not be administered during pregnancy & lactation due to reports that small amounts of Diacerein derivatives pass into the maternal milk. Patients should consult with their physician before taking any medicine.

Patients should consult with their physician before taking any medicine.